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Cytokines in Inflammatory Bowel Disease (Medical Intelligence Unit) ePub download

by Claudio Fiocchi

  • Author: Claudio Fiocchi
  • ISBN: 0412100517
  • ISBN13: 978-0412100512
  • ePub: 1264 kb | FB2: 1324 kb
  • Language: English
  • Category: Medicine
  • Publisher: Chapman & Hall (January 1, 1996)
  • Pages: 270
  • Rating: 4.4/5
  • Votes: 287
  • Format: mbr rtf docx lit
Cytokines in Inflammatory Bowel Disease (Medical Intelligence Unit) ePub download

The focus of investigation in inflammatory bowel disease (IBD) is almost invariably centered on the various cellular and soluble components of the mucosal immune system whose abnormal number or functions presumably underlies the pathogenesis of chronic intestinal inflammation.

The pathogenesis of both forms of inflammatory bowel disease, Crohn"s disease and ulcerative colitis, depends on. .

The pathogenesis of both forms of inflammatory bowel disease, Crohn"s disease and ulcerative colitis, depends on complex immune abnormalities, and the investigation of cytokines has become critical to basic, clinical and therapeutic aspects of these enigmatic entities. This book offers clear, concise, state-of-the-art information on the role of various immunoregulatory and pro-inflammatory mediators in Crohn"s disease and ulcerative colitis.

0 Cytokines in Inflammatory Bowel Disease Claudio Fiocchi, Case Western Reserve University. 0 TCell Vaccination and Autoimmune Disease JingwuZhang, Willems lnstitut-Belgium. Pnina Brodt, McGill University. 0 Constitutional Immunity to Infection Gees M. Verduin, DavidA. Watson, Jan Verhoef, Hans Van Dijk, University ofUtrechtandNorth Dakota State University. 0 Nutritional and Metabolic Support in Critically Ill Patients.

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Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the colon and small intestine. Crohn's disease and ulcerative colitis are the principal types of inflammatory bowel disease. Crohn's disease affects the small intestine and large intestine, as well as the mouth, esophagus, stomach and the anus, whereas ulcerative colitis primarily affects the colon and the rectum.

Cytokines in in¯ ammatory bowel disease P. L. Beck and J. WallaceCA.

Keywords: inflammatory bowel disease, ulcerative colitis, Crohn’s disease, systems biology, network medicine, complexity, variability.

Inflamm Bowel Dis (2017) 23(9):1499–509. PubMed Abstract CrossRef Full Text Google Scholar. Keywords: inflammatory bowel disease, ulcerative colitis, Crohn’s disease, systems biology, network medicine, complexity, variability. Citation: Fiocchi C (2018) Inflammatory Bowel Disease: Complexity and Variability Need Integration.

Inflammatory bowel disease. Podolsky DK1. Author information. Inflammatory bowel disease.

Cytokines play a central role in the modulation of the intestinal immune system. Mucosal and systemic concentrations of many pro- and antiinflammatory cytokines are elevated in inflammatory bowel disease (IBD)

Cytokines play a central role in the modulation of the intestinal immune system. They are produced by lymphocytes (especially T cells of the Th1 and Th2 phenotypes), monocytes, intestinal macrophages, granulocytes, epithelial cells, endothelial cells, and fibroblasts. Mucosal and systemic concentrations of many pro- and antiinflammatory cytokines are elevated in inflammatory bowel disease (IBD). An imbalance between proinflammatory and antiinflammatory cytokines was found for the IL-1/IL-1ra ratio in the inflamed mucosa of patients with Crohn's disease, ulcerative colitis, diverticulitis, and infectious colitis.

Consultant for Abbvie.

Biologics in inflammatory bowel disease Therapeutic mAbs have become a fundamental tool for the management of numerous diseases. Over 300 products of this type are currently under development, and approximately 30 others have already been approved in the United States Paolo Gionchetti: IBD Unit, Dept of Medical and Surgical Sciences, S. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy. Speaker, consultant or advisory board member for Abbvie, MSD, Ferring, Takeda, Nycomed, Sofar, Chiesi, Hospira. Consultant for Abbvie.

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